Mitophagy and clear cell renal cell carcinoma: insights from single-cell and spatial transcriptomics analysis
BackgroundClear Cell Renal Cell Carcinoma (ccRCC) is the most common type of kidney cancer, characterized by high heterogeneity and complexity.Recent studies have identified mitochondrial defects and autophagy as key players in the development of ccRCC.This study aims to delve into the changes in mitophagic activity within ccRCC and its impact on t